The Three Musketeers
Success of the individual musketeers is overly dependent on the success of the other two musketeers.

To Kill a Mockingbird
Missing detailed IACUC protocol for mockingbird euthanasia.

Moby-Dick
Fishing expedition.

Of Mice and Men
PI lacks expertise in both systems.

Great Expectations
Overly ambitious.

One Hundred Years of Solitude
Unlikely to complete studies within a 4-year time frame.

One Flew Over the Cuckoo’s Nest
Statistically underpowered.

The Sun Also Rises
Hypothesis already well established.

A Tale of Two Cities
Unclear how studies will be coordinated between the two sites.

Dune
Though intriguing, sand worms have not yet proven to be a genetically tractable system.

A Farewell to Arms
Limb regeneration fascinating but concerns regarding relevance of amphibian systems persist.

Where the Red Fern Grows
Why should the NIH fund a plant study?

Much Ado about Nothing
Significance?

The Lion, the Witch and the Wardrobe
Aims come across as disconnected.

I Know Why the Caged Bird Sings
Needs to consider alternative hypotheses.

Fifty Shades of Gray
How many new fluorescent proteins do we really need?

The Hunger Games
Human subject protocols questionable.

Paradise Lost
PI recently failed to renew Howard Hughes and needs an R01.

Cat’s Cradle
Concerns regarding biosafety containment.

All Quiet on the Western Front
Hasn’t demonstrated ability to express proteins of interest.

Remembrance of Things Past
Accomplished PI but recent productivity has been modest.

To a God Unknown
The PI has responded well to previous critiques.

The Little Engine That Could
The PI has stubbornly argued previous critiques because they “think they can.”